I think that everyone has a time in their life when they feel alone or lost, or even out of touch from those around them. The labyrinth represents a puzzle that we are driven to solve. It also represents our stubbornness to accept that help when we need it most.
The design of a knot is like a labyrinth, a maze of crossing lines and paths, eternally connected with no end and no beginning. The knot is symbolic of life as an endless labyrinth. It also represents a guide or map to the labyrinth which is constantly available to us if we will only look toward it.